FRESHFROZENPLASMA

Indications & Dose:

Replacement of coagulation factors or other plasma proteins where their concentration or functional activity is critically reduced%BY INTRAVENOUS INFUSION%Adult: (consult haematologist)Major bleeding in patients on warfarin following phytomenadione (if dried prothrombin complex isunavailable)% Adult: 15 mL/kilogram

Contraindications:

Avoid use as a volumeexpander .IgA deficiency with confirmed antibodies to IgA 

Side Effects:

%Common or very common Nausea . pruritus . rash%Uncommon Oedema . vomiting%Rare Agitation . allergic reactions . bronchospasm cardiorespiratory collapse . chills fever . tachycardia%Very rare Arrhythmia . hypertension . thromboembolism

Cautions:

Cardiac decompensation . need for compatibility . pulmonary oedema . severe protein deficiency

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