Clinical Pharmacology Details


OMEGA-3-ACIDETHYLESTERS


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Indications & Dose:

Adjunct to diet and statin in type IIb or III hypertriglyceridaemia | Adjunct to diet in type IV hypertriglyceridaemia



Adult: Initially 2 capsules daily, dose to be taken with food, increased if necessary to 4 capsules daily


Adjunct in secondary prevention in those who have had a myocardial infarction in the preceding 3 months



Adult: 1 capsule daily, dose to be taken with food 

Contraindications:

Side Effects:

Common or very common Dyspepsia . nausea


Uncommon Abdominal pain . dizziness . gastritis .taste disturbances


Rare Acne . headache . hepatic disorders . hyperglycaemia . rash


Very rare Gastro-intestinal haemorrhage . hypotension . increased white cell count . nasal dryness . urticari


PREGNANCY Manufacturers advise use only if potential benefit outweighs risk—no information available.


BREAST FEEDING Manufacturers advise avoid— no information available.


HEPATIC IMPAIRMENT Monitor liver function in hepatic impairment.


 

Cautions:

Anticoagulant treatment (bleeding time increased) . haemorrhagic disorders

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: