DIPHENHYDRAMINE+AMMONIUM CHLORIDE

Indications & Dose:

Perennial and seasonal allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis; symptomatic relief of common cold; allergic and nonallergic pruritic symptoms; uncomplicated allergic skin manifestations of urticaria and angioedema; adjunctive therapy of anaphylactic reactions; motion sickness; sleep aid; parkinsonism (including drug-induced); cough suppressant; acute dystonic reactions

DOSE

5-10mg 2-3 times daily. 

Contraindications:

Narrowangle glaucoma, bladder neck obstruction 

Side Effects:

CNS: Anxiety; confusion, dizziness, drowsiness, euphoria, fatigue, neuritis, paresthesia, poor coordination

CV: Palpitations, tachycardia

EENT: Blurred vision, dilated pupils, dry nose, throat, nasal stuffiness, tinnitus

Gl: Anorexia, constipation, diarrhea, dry mouth, nausea, vomiting

GU: Dysuria, frequency, impotence, retention

HEME: Bone marrow suppression, hemolytic anemia

RESP: Chest tightness, increased thick secretions, wheezing

SKIN: Photosensitivity, rash, urticaria; topical preparations can sensitize the skin 

Cautions:

Precautions:

Liver disease, elderly, increased intraocular pressure, hyperthyroidism, cardiovascular disease, hypertension, urinary retention, renal disease, stenosed peptic ulcers 

Interaction:

Drugs

Anticholinergics: Possible enhanced anticholinergic, CNS effects

Labs

• False negative: Skin allergy tests

• False positive: Urine methadone, serum and urine tricyclic antidepressant

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: