Clinical Pharmacology Details


PHENIRAMINE MALEATE


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Indications & Dose:

 Symptomatic relief of allergy such as hay fever, urticaria, food allergy, drug reactions Relief of itch associated with chickenpox 



Inj. according to the severity of cases.


Adults


1/2, amp i/v (1ml/min) or i/m once or twice a day:



Tabs: : Initially 1/2 to 1tab 2-3 times daily, if necessary 1 tab 3 times daily from the second day of treatment onwards.


Syp:2-4 tsf 3 times daily.


Children


6 months-3 years, 0.4 -1ml im once or twice a day.


Over 4 years old, 0.8 2ml i/m once or twice a daily.


Syp:1-2 tsf 3 times daily

Contraindications:

Hypersensitivity of pheniramine/prostatic hypertrophy and a tendency towards residual urine formation and pregnancy, treatment of patients with narrow angle glaucoma under ophthalmologists supervision only.  Patients with alertness demanding activities because of possible drowsiness. 

Side Effects:

Dryness of mouth, urine retention, increase in intraocular pressure, gastrointestinal upset, palpitation after high doses, hallucination, agitation and disorientation 

Cautions:

Hepatic & renal dysfunction. 

Precautions:

Interaction:

Drugs


Same as Triprolidine 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: