KETOTIFEN

Indications & Dose:

Allergic rhinitis

• BY MOUTH

Child 3–17 years: 1 mg twice daily

Adult: 1 mg twice daily, increased if necessary to 2 mg twice daily, to be taken with food

Allergic rhinitis in readily sedated patients

• BY MOUTH

Adult: Initially 0.5–1 mg once daily, dose to be taken at night

OR

Adults

1-2mg twice daily with food. Initial treatment in readily sedated patients 0.5-1mg at nigh, may be increased upto 4mg.

Children

6 month to three years; 0.05mg (=0.25ml syp)/kg body weighttwice daily with meal, 3 years and above; 5ml (1 teaspoonful) or 1 tablet of 1mg twice daily, with meal

Contraindications:

Hypersensitivity, glaucoma.

Side Effects:

Drowsiness, dry mouth, slight dizziness, CNS stimulation, weight gain also reported. 

Cautions:

Previous anti-asthmatic treatment should be continued for a minimum of 2 weeks after initation of ketotifen treatment; avoid with oral antidiabetics (fall in thrombocyte count reported). Driving drowsiness may affect performance of skilled tasks (e.g. driving), effects of alcohol enhanced. 

Precautions:

Previous antiasthmatic treatment should be continued for a maximum of 2 weeks after initiation of ketotifen treatment.

Old age: May be used. 

Interaction:

Drugs

Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. Oral antidiabetics: Avoid as fall in thrombocyte count reported. 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Withdraw over 2-4 weeks pregnancy, lactation, history of epilepsy

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: