DONEPEZIL HYDROCHLORIDE

Indications & Dose:

Mild to moderate dementia in Alzheimer’s disease

• BY MOUTH

Adult: Initially 5 mg once daily for one month, then increased if necessary up to 10 mg daily, doses to be given at bedtime

Contraindications:

Side Effects:

CNS: Abnormal dreams, depression, dizziness, fatigue, headache, insomnia, somnolence

CV: Syncope

CI: Anorexia, diarrhea, nausea, vomiting

GU: Frequent urination

HEME: Ecchymosis

METAB:  Weight decrease

MS: Arthritis, muscle cramps

Cautions:

Precautions:

Sick sinus syndrome or other supraventricular cardiac conduction conditions, history of peptic ulcer disease, bladder outflow obstruction, seizure disorder, asthmal COPD 

Interaction:

Drugs

Fluvoxamine: Possible increase in fluvoxamine levels 

Warnings:

Adverse Effects:

Lactations:

Pregnancy category C 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: