BUSPIRONE hydrochloride

Indications & Dose:

Anxiety (short-term use)

• BY MOUTH

Adult: 5 mg 2–3 times a day, increased if necessary up to 45 mg daily, dose to be increased at intervals of 2–3 days; usual dose 15–30 mg daily in divided doses

Children: Not recommended. 

Contraindications:

Side Effects:

Cautions:

Precautions:

Liver disease, renal disease, elderly, children < 18 yr 

Interaction:

Drugs

Fluoxetine: Reduced therapeutic response to both drugs

Warnings:

Adverse Effects:

Lactations:

Excretion into breast milk unknown; use caution in nursing mothers 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Akathisia, confusion, depresssion, dizziness, drowsiness, excitement, headache, incoordination, insomnia, involuntary movements, lightheadedness, nervousness, paresthesia, stimulation, tremor

CV: Bradycardia, hypertension, hypotension, nonspecific chest pain, palpitations

EENT: Altered taste, smell; blurred vision; nasal congestion; red, itchy eyes; sore throat; tinnitus

GI: Constipation, diarrhea, dry mouth, dyspepsia, flatulence, increased appetite, nausea, rectal bleeding

GU: Change in libido, frequency, hesitancy, menstrual irregularity

MS: Muscle craps, pain, spasms, weakness

RESP: Chest congestion, hyperventilation, shortness of breath

SKIN: Alopecia, dry skin, edema, pruritus, rash

MISC: Fatigue, fever, sweating, weight gain 

Patient And Carer Advice: