ZUCLOPENTHIXOL

Indications & Dose:

Schizophrenia and other psychoses

• BY MOUTH

Adult: Initially 20–30 mg daily in divided doses, increased if necessary up to 150 mg daily; usual maintenance 20–50 mg daily (max. per dose 40 mg), for debilitated patients, use elderly dose

Elderly: Initially 5–15 mg daily in divided doses, increased if necessary up to 150 mg daily; usual maintenance 20–50 mg daily (max. per dose 40 mg)

• BY INJECTION

Adult: Usually 200-400mg by deep IM injection every two to four weeks; maximum 600mg a week.

Children: Not recommended. 

Contraindications:

Acute alcohol, barbiturate, the opiate intoxication, comatose  states

Side Effects:

Cautions:

Precautions:

Used with caution in patients with convulsive disorders or advanced hepatic or cardiovascular diseases. Should not be administered during pregnancy.

Interaction:

Not be given concomitantly with guanethidine or similar acting compounds, since neuroleptics may block the antihypertensive effect of these compounds. May lower the effect of levodopa and adrenergic drugs and concomitant use of metoclopramide and piperazine increases the risk of extrapyramidal symptoms. 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: