HALOTHANE

Indications & Dose:

Induction and maintainance of anaesthesia. In operations where bloodless field is required.

Adults:

Induction: upto 5% in air, oxygen or oxygen/nitrous oxide. maint.: 0.5-2%.

Children:

1.5—2.0% in O2 mixture or O2/N2OMaintainance: 0.5—2.0% in O2 or O2/N2O mixture

Contraindications:

Un-explained jaundice following previous exposure. 

ADVANTAGES:  Rapid smooth induction, non irritant to respiratory tract, may produce branchodilatation, relatively rapid recovery.

DISADVANTAGES:

Poor analgesic properties, may cause uterine relaxation leads to haemorrhagic in  obstetric patients, hypotension,  dysrhythmia, shivering, tremors, possibility of hepatotoxicity.

Side Effects:

Moderate fall of blood pressure commonly during induction. Cardiac arrythmias and malignant hyperpyrexia have been reported, liver damage. Halothane hepatitis, hepatic necrosis, shivering during recovery. 

Cautions:

Precautions:

 Maintain in lightest plane possible in obstetric practice used moderate hyperventilation during neurosurgery. Adrenaline may precipitate dysrrhy- thmias. Avoid repeated exposure within three months. Ensure adequate room ventilation. Avoid during early pregnancy unless essential lactation  has been detec-ted in breast milk. Ability to drive or operate machinary may be impaired.

PREGNANCY: Use only if potential benefit outweighs risk to the foetus.

BREAST-FEEDING: Use with caution.

OLD AGE: May be given in reduced dose. 

Interaction:

Drug

Non depolarising muscle relaxants 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: