ISOFLURANE

Indications & Dose:

For rapid induction & recovery of anaesthesia.

Induction:  increased gradually from 0.5% to 3%, in oxygen or nitrous oxide-oxygen

Maintenance: 1-2.5% in nitrous oxide-oxygen, an additional 0.5-1% may be required when given with oxygen alone; caesarean section, 0.5-0.75% in nitrous oxide-oxygen

ADVATAGES: Rapid induction & recovery, minimal biotransformation with little risk of hepatic and renal toxicity, cardiovascular stability, muscle relaxation

DIS ADVANTAGES: High cost, a pungent  odour, coronary vasodilater 

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