ROCURONIUM BROMIDE

Indications & Dose:

Neuromuscular blockade (intermediate duration) during surgery and intubation

• INITIALLY BY INTRAVENOUS INJECTION

Adult: Initially 600 micrograms/kg; (by intravenous injection) maintenance 150 micrograms/kg, alternatively (by intravenous infusion) maintenance 300–600 micrograms/kg/hour, adjusted according to response

Elderly: Initially 600 micrograms/kg; (by intravenous injection) maintenance 75–100 micrograms/kg, alternatively (by intravenous infusion) maintenance up to 400 micrograms/kg/ hour, adjusted according to response

Neuromuscular blockade (intermediate duration) during intensive care

• INITIALLY BY INTRAVENOUS INJECTION

Adult: Initially 600 micrograms/kg, initial dose is optional; (by intravenous infusion) maintenance 300–600 micrograms/kg/hour for first hour, then (by intravenous infusion), adjusted according to response

DOSES AT EXTREMES OF BODY-WEIGHT

To avoid excessive dosage in obese patients, dose should be calculated on the basis of ideal bodyweight. 

Contraindications:

Former anaphylactic reactions to rocuronium or to the bromide ions 

Side Effects:

Cautions:

Hepatic and renal impairment. 

Precautions:

Administered only with general anaesthesia and under the closed supervision of an experienced anaesthesist and adequate facilities for endotracheal intubation and artificial vetilation. 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: