Clinical Pharmacology Details


Nefopam Hcl


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Indications & Dose:

Moderate pain. Acute and chronic pain, including post operative, dental, cancer, musculoskeletal, traumatic pain. Pain in opioid addicts.


Adults 30-90mg, 3 times a day.


Elderly Initially 30mg thrice daily. Inj: 20mg i.m. repeated after 6 hrs if req-uired.


Children Not recommended. 

Contraindications:

Children, history of epilepsy and myocardial infarction.

Side Effects:

 Nausea, nervousness, urinary retention, dry mouth, light-headedness;  less frequently vomiting, blurred vision, drowsiness, sweating,  insomnia, tachycardia, headache; confusion and hallucinations also reported; may colour urine (pink).


 

Cautions:

 Hepatic  and  renal  disease, elderly, urinary retention. 

Precautions:

Hepatic and renal dysfunction. Urinary retention. Pregnancy: Safety not established. Breast-feeding: Use with caution. Old age: May be given in reduced dose. 

Interaction:

 Drugs 


See under Orphenadrine.

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: