CEFPROZIL

Indications & Dose:

Infections of the upper and lower respiratory tract (pharyngitis, tonsillitis, otitis media, secondary bacterial infection of acute bronchitis, acute bacterial exacerbation of chronic bronchitis); skin and skin structure due to susceptible organisms 

DOSAGE

Adult

Otitis media: 15mg/kg every 12 hour

Upper respiratory tract infections: 20mg/kg once daily  or 15mg/kg into two equal divided doses.

Sinusitis: 7.5mg/kg to 15mg/kg every 12 hours

Child 6 mo-12 yr

• Upper respiratory tract infections:PO 7.5 mg /kg q 12h x 10 days

• Otitis media: PO 15 mg/kg q12hx10 days

• Skin/skin structure infections: PO 20 mg/kg qd x 10 days 

Contraindications:

Side Effects:

CNS: Chills, dizziness, fever, headache, paresthesia, weakness

GI: Abdominal pain, anorexia, bleeding; diarrhea, flatulence; glossitis, increased LFTs; pseudomembranous colitis, vomiting

GU: Candidiasis, genitoanal pruritus, hematuria, nephrotoxicity, vaginitis

HEME: Bone marrow suppression, eosinophilia, hemolytic anemia, lymphocytosis

SKIN: Dennatitis, rash , urticaria

RESP: Dyspnea 

Cautions:

Precautions:

 Elderly, hypersensitivity to penicillins 

Interaction:

Drugs

Aminoglycosides: Additive nephrotoxicity

Loop diuretics Increased nephrotoxicity

Warnings:

Adverse Effects:

Lactations:

Pregnancy category B 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: