Clinical Pharmacology Details


Trifluoperazine + Isopropamide


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Indications & Dose:

In the treatment of a wide range of gastrointestinal disorders including peptic ulcer, hyperchlorhydria, gastritis and duodenitis, pylorospasm, gastrointestinal spasm, biliary dyskinesia,, chronic cholelithiasis, mucous colitis,, irritable or spastic colon, functional, diarrhea, and spastic constipation.



Adult :One tablet every 12 hour.


Children: Not recommended.


 


 


 

Contraindications:

 In comatose states and in the presence of glaucoma, card iospasm, pyloric obstruction of organic origin, prostatic hypertrophy, or obstruction at the bladder neck.

Side Effects:

Possible anticholinergic side effects are constipation, dryness of the mouth, blurred vision and urinary hesitancy. Because of the low dosage of the component, neuromuscular (extrapyramidal) symptoms are not to be expected, but such reactions may occur in patients sensitive to phenothiazine compounds.

Cautions:

Precautions:

Should be used with caution in patients suffering from cardiac impairment and, in pregnant patients, especially during the first trimester. Because  has a potent antiemetic effect, it may mask signs of overdosage of toxic drugs and may obscure diagnosis of such conditions as intestinal obstruction and brain tumor.


 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: