ETHIONAMIDE

Indications & Dose:

Treatment and prophylaxis of tuberculosis; where other therapy is contraindicated  or ineffective

DOSE

Adult: Resistant tuberculosis: 0.5-1g daily after meal in 2-3 divided doses along with other therapy , max; 1g daily., Multibacillary leprosy ; 5mg/kg daily as a single dose.

Childrens:

 Resistant tuberculosis: 15-20mg/kg /day 12 hourly , max 1g daily. Multibacillary leprosy ; Same as adult on weight basis

Contraindications:

Acute liver disease and hypersensitivity.

Side Effects:

Cautions:

Precautions:

To assess liver function periodically 

Interaction:

Drugs

Not known 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Nausea, vomiting , anorexia, hepatotoxicity, drowsiness, depression, peripheral neuritis, headache, skin rash, menorrhagia, acne, alopecia, hypertention, convulsion, diplopia 

Patient And Carer Advice: