MEFLOQUINE

Indications & Dose:

Primarily indicated in conditions like Adjunctive therapy without valproate, Malaria caused by plasmodium falciparum, Malaria caused by plasmodium vivax, Malaria prophylaxis, To reduce degradation of pancreatic enzyme supplements, Uncomplicated malaria.

• BY MOUTH

Adult: 250.000 mg Weekly. For Malaria Prophylaxis, 1250.000 mg in 24 hour as single dose For Malaria treatment. Paedriatic Dosage ( 20 Kg. ) 25.000 mg/kg as single dose in 24 hour. 

Contraindications:

contraindicated in conditions like Epilepsy, Psychiatric disease, Hypersensitivity. 

Side Effects:

Convulsions, Hallucinations, Hallucinations, Seizures, Behavioral disorders. Life-threatening effects which include Aplastic Anemia, Exfoliative dermatitis, Aplastic anemia, Cutaneous vasculitis. which are responsible for the discontinuation of Mefloquine (HCl) therapy. After the acute overdosage: GI disturbances, Psychosis.

The symptomatic adverse reactions : Dizziness, Headache, Nausea, Vomiting, Anorexia, Diarrhea, Constipation, Urticaria, Pruritus, VertigoX, Asthenia, Arthralgia, Sinus bradycardia, Stomachache, Hearing disturbances, Pulse irregularities, Sialorrhea. 

Cautions:

Precautions:

used with caution in patients with any psychiatric disorders, heart problems, seizure disorders and any allergy, especially allergy to other drugs. It should be used with caution in children. It should be used only when clearly needed during pregnancy or lactation. 

Interaction:

Mefloquine (HCl) is known to interact with other drugs like Amiodarone (HCl), Artemisinin, Chloroquine, Dihydroartemisinin, Halofantrine (HCl), Quinidine, Quinine, Sulfadoxine. 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: