FAMCICLOVIR

Indications & Dose:

• BY MOUTH

Adult

• Herpes zoster:

250mg 3 times daily for 7 days  or 750mg once daily for 7 days ( immunocompromised 500mg three times daily for 10 days)

• Genital herpes simplex:

250mg 3 times daily for 5 days; if CrCI 20-39 ml/ min, use 125 mg q24h for 5 days; if CrCI <20 ml/ min, use 125 mg q48h for 5 days

• Suppression of genital herpes:

250 mg bid; if CrCI 20-39 ml/min, use 125 mg q 12h; if CrCI <20 ml/min, use 125 mg q24h

Child:Not recommended 

Contraindications:

Side Effects:

Cautions:

Precautions:

 Renal insufficiency, children 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Pregnancy category B; excreted in breast milk 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Bradykinesia, confusion, dizziness, headache, somnolence

GI: Anorexia, constipation, diarrhea (8%), nausea (13%)

MS: Arthralgia

SKIN: Pruritus, purpura 

Patient And Carer Advice: