TELBIVUDINE

Indications & Dose:

Chronic hepatitis B infection with compensated liver disease, evidence of viral replication, and histologically documented active liver inflammation or fibrosis.   

• BY MOUTH

•ADULT and CHILD Over 16 years, 600mg once daily

Contraindications:

 breast-feeding 

Side Effects:

nausea, diarrhoea, abdominal pain, raised serum amylase and lipase; cough; dizziness, headache, fatigue; rash; less commonly arthralgia, myalgia, and rnyopathy 

Cautions:

monitor liver function tests every 3 months and viral and serological markers of hepatitis B every 3—6 months; discontinue if deterioration in liver function, hepatic steatosis, progressive hepatomegaly or unexplained lactic acidosis; recurrent hepatitis may occur on discontinuation;renal impairment ; pregnancy

COUNSELLING: Patients should be advised to promptly report unexplained muscle pain, tenderness or weakness 

Precautions:

Interaction:

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Lactations:

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Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: