INTERFERON ALFA-2A

Indications & Dose:

Hairy cell leukemia (in splenectomised and nonsplenectomised) and AIDS related Kaposi’s sarcoma in patients above 18 years. DOSE Adults Hairy cell leukemia Induction: 3 million i.u. daily for 16-24 weeks s/c or i/m. Maint. 3 million i.u. 3 times per week. Treat for approx. 6 months. Kaposi’s sarcoma: 36 million i.u. daily for 10-12 weeks i/m s/c. Maint. 36 million i.u. 3 times/wk. Children Not recommended. 

Contraindications:

Hypersensitivity to alpha interferon or any of the component. 

Side Effects:

GI haemorrhage, decreased mental status, leukopenia and elevation of liver enzymes.

Cautions:

Precautions:

Administer with caution to patient with cardiac disease. Depression and suicidal behaviour.
Pregnancy: Use with caution.
Breastfeeding: Discontinue nursing or the drug.
Old age: May be given in reduced dose. 

Interaction:

Drugs
Theophylline: Inhibits metabolism 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: