RIBAVIRIN / TRIBAVIRIN

Indications & Dose:

Severe lower respiratory tract infection by RSV in children (if begun within 1st 3 days of infection), influenza A, influenza B, hepatitis C (combination with interferon alfa-26), Lasso fever, hantavirusassociated hemorrhagic fever

• BY MOUTH

Adult

Chronic Hepatitis C: Adult: over 18 years body weight under 65kg 400mg twice daily, body weight 65-85kg 400mg in the Morning and 600mg in the Evening. Body Weight over 85mg/ kg 600mg twice daily.

Children: 15-20mg/kg Body weight in 3 divded doses for 5.7 days. 

Contraindications:

Pregnancy and females of childbearing age. 

Side Effects:

Cautions:

Precautions:

Patients receiving mechanical ventilation 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Teratogenic in animals; contraindicated in lactating women 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Headache, seizures (systemic administradon only)
CV: Cardiac arrest, hypotension
EENT: Conjunctivitis
GI: Anorexia, increased transaminases (systemic administration only), nausea
HEME: Anemia, reticulocytosis
RESP: Apnea, bacterial pneumonia, pneumothorax, worsening of respiratory status
SKIN: Rash

Patient And Carer Advice: