Cushing’s Syndrome - Enzyme Inhibitors - Ketoconazole

Indications & Dose:

Endogenous Cushing’s syndrome (specialist use only)

BY MOUTH Adult: Initially 400–600 mg daily in 2–3 divided doses, increased to 800–1200 mg daily; maintenance 400–800 mg daily in 2–3 divided doses, for dose titrations in patients with established dose, adjustments in adrenal insufficiency, or concomitant corticosteroid replacement therapy, consult product literature; maximum 1200 mg per day.

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