Sitagliptin

Indications & Dose:

Type II diabetes mellitus.
BY MOUTH Adult Dosage: 100mg 24 hourly oral (take with or without food. If drug bothers your stomach, try taking it with food. Children: Not Recommended.

Contraindications:

Trauma, Diabetic ketoacidosis, Insulin dependent diabetes mellitus, Severe infections, Type I diabetes mellitus.
CONTRAINDICATIONS Diabetic ketoacidosis, hypersensitivity to sitagliptin or its components, type 1 diabetes

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Adverse Effects:

CNS: Headache EENT: Nasopharyngitis
GI: Abdominal pain, acute pancreatitis, constipation, diarrhea, elevated hepatic enzymes, nausea, vomiting
GU: Acute renal failure, worsening renal function
RESP: Upper respiratory tract infection
SKIN: Cutaneous vasculitis, rash, StevensJohnson syndrome, urticaria Other: Anaphylaxis, angioedema 

Lactations:

DRUGS
ACE inhibitors, disopyramide, fibric acid derivatives, fluoxetine, sulfonylureas: Possibly increased hypoglycemic effects beta blockers: Possibly prolonged hypogly-cemia or promotion of hyperglycemia digoxin: Slightly increased plasma digoxin level estrogens, oral contraceptives, phenytoin, progestins, thiazide diuretics, triamterene: Possibly decreased hypoglycemic effects

Special Precautions:

Counselling:

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Patient And Carer Advice: