Risedronate

Indications & Dose:

Adults :

Paget’s Disease:

• BY MOUTH

35 mg dailyx2 months

• Post menopausal Osteoporosis (prophylaxis):

• BY MOUTH

PO 35 mg once weekely on the same day of each week

• Post menopausal women on systemic corticosteroids therapy:

• BY MOUTH

5mg tab daily

Child: Not recommended

Contraindications:

Hypocalcemia

Side Effects:

CV: Chest pain 
EENT: Iritis, dry eyes 
GI: Diarrhea (20%); epigastric pain (rarely) 
MS: Arthralgia, myasthenia 

Cautions:

Precautions:

Renal impairment, congestive heart failure, hyperphosphatemia (potential for increased tubular reabsorption of phosphate), liver disease, fever 

Interaction:

Drugs

Antacids, calcium: decreased absorption of risedronate

Food: decreases bioavailability of risedronate by 50%

Warnings:

Adverse Effects:

Lactations:

Pregnancy category C; breast milk excretion unknown 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: