Clinical Pharmacology Details


Phosphate Binders Sevelamer Hydrochloride


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Indications & Dose:

Management of hyperphosphataemia in adult patients with stage 4 and 5 chronic renal failure on hemodialysis.


By mouth :


12-18 years 0.8-1.6g three times daily with meal than adjusted according to plazma phosphate concentration. 

Contraindications:

in hypophosphataemia or bowel obstruction. 

Side Effects:

Cautions:

Precautions:

Interaction:

Warnings:

Adverse Effects:

Common adverse drug reactions (ADRs) associated with the use of sevelamer include: hypotension, hypertension, nausea and vomiting, dyspepsia, diarrhea, flatulence, and/or constipation.


Other effects Sevelamer can significantly reduce serum uric acid, This reduction has no known detrimental effect and several beneficial effects, including reducing hyperuricemia, uric acid nephrolithiasis, and gout

Lactations:

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Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: