Clinical Pharmacology Details


Vitamin C (ASCORBIC ACID)


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Indications & Dose:

Adults
Prophylaxis:
50-500mg daily.
Pregnancy and lactation: 100-150mg daily.
Treatment: Upto 1000mg daily.
Scurvy: 1g 2-3 times daily.
Children: 30-100mg daily. Scurvy: 300mg-1gm daily.
Drops:
Infants:
2 drops twice daily. 

Contraindications:

Hypersensitivity to Vit C 

Side Effects:

 Diarrhea, may cause precipitation of oxalate or  renal stones if urine becomes acidic during therapy. 

Cautions:

i/v incompitability, Vit C is chemically incompatible with potassium peniullir G.
Pregnancy: Give only if clearly needed.
Breastfeeding: Use with caution. 

Precautions:

Interaction:

Drugs
Oral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions.
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab. Tests: Large doses (>500mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests. 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: