Cetuximab

Indications & Dose:

In combination with irinotecan for the treatment of epidermal growth factor receptor-ex-pressing metastatic colorectal cancer after failure of irinotecan-containing therapy. In combination with radiotherapy for the treatment of locally advanced squamous cell cancer of the head and neck.

DOSAGE:

Metastatic colorectal carcinoma: Adults: Initial: 400 mg/square meter IV infusion over 120 min.Maintenance: 250 mg/square meter IV infusion over 60 min once weekly. Mas infusion Rate: 5 mL/min. Children: Not recommended.

ADMINISTRATION: Do not administered as an IV push or bolus. Administered via inf pump or syringe pump. Administer initial dose over 120 minutes, then administer subsequent dose over 60 minutes. The maximum inf rate is 5 mL/min (10 mg/min).

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