Dacarbazine

Indications & Dose:

Malignant melanoma, Hodg-kin’s disease, soft tissue sarcomas., testicular tumours, colorectal cancer, tumour of G.I. tract. l

• BY INTRAVENOUS INFUSION, OR BY INTRAVENOUS INJECTION

Adult: (consult local protocol) AND PRODUCT LITERATURE 

Contraindications:

Previous severe myelosuppression.
Pregnancy & breast-feeding.

Side Effects:

Nausea, vomiting, diarrhea, anaphylaxis, bone marrow depression, alopecia, urticrial rash, photosensitivity, hepatic necrosis, renal impairment, thrombocytopenia, blurred vision, flu like syndrome, myalgias and malaise

Cautions:

Precautions:

Hepatic/renal impairment, skin and eye contact, haematological monitoring and restrict food intake 4-6 hours prior to therapy.
Old age: Use with caution.

Interaction:

Drugs Phenobarbital, Acathio-prim 6MP.

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: