Clinical Pharmacology Details


Eflornithine Hydrochloride


View Drug Forms

Indications & Dose:

Facial Hirsutism in Women: Apply thiny two times daily/ Rubbed gently and throughly over affected area. Do not wash for 4 hours after application. Cosmetic may be appllied after 5 minutes


Incompatibilities


Don’t give eflornithine with any other drug.

Contraindications:

Hypersensitivity to eflornithine or its components

Side Effects:

Cautions:

Precautions:

General


For external use only.


Transient stinging or burning may occur when applied to abraded or broken skin..

Interaction:

Warnings:

Discontinue use if hypersensitivity occurs.

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Asthenia, dizziness, headache, seizures
EENT: Hearing loss
GI: Abdominal pain, anorexia, diarrhea, vomiting
HEME: Anemia, eosinophilia, leukopenia, myelosuppression, thrombocytopenia
Other: Alopecia, facial edema


•Consult prescriber about the need for serial audiography, if appropriate.


• Store undiluted vials of eflornithine at room temperature, and protect from freezing and light.

Patient And Carer Advice: