Clinical Pharmacology Details


Haemophilus influenzae type b, diphtheria, tetanus and pertussis


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Indications & Dose:

INIDICATIONS:


Combined prevention, from 2 months of age, of invasive disease caused by Haemophilus influenzae type b, diphtheria, tetanus and pertussis.


DOSE:


The preferred route of administration in intramuscular although it may also be given subcutaneously, after reconstitution of the freezedried PRP-T with the injectable suspension of D.T.P.


Primary immunization: From 2 months of age: 3 injection.


Booster injection: 1 injection 12 months after the 3rd injection. 

Contraindications:

 Acute illness. History of convulsions, cerebral irritation or damage in the neonatal period. Severe local or general reaction to a preceding dose. Neurological disease.

Side Effects:

Cautions:

Precautions:

 History of familial epilepsy. Children with history of severe local reaction to a preceding dose should be given DPT in one limb and HiB in another.

Interaction:

Warnings:

Adverse Effects:

Local pain, fever, irritability, persistent crying, headache, loss of appetite; malaise, somnolence, allergy, neurological effects. 

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: