Phenylephrine

Indications & Dose:

Mydriasis

• TO THE EYE

Child: Apply 1 drop, to be administered before procedure, a drop of proxymetacaine topical anaesthetic may be applied to the eye a few minutes before using phenylephrine to prevent stinging

Adult: Apply 1 drop, to be administered before procedure, then apply 1 drop after 60 minutes if required, a drop of topical anaesthetic may be applied to the eye a few minutes before using phenylephrine to prevent stinging

Contraindications:

10% strength eye drops  children and the elderly . aneurysms . cardiovascular disease . hypertension . thyrotoxicosis

Narrow-angle glaucoma

DOSE

Adult and Child 1-2 drops 2-3 hourly for 2 days, then one instilation 3 times daily for 5-6 days.

Side Effects:

Arrhythmias . blurred vision . conjunctivitis on prolonged administration . coronary artery spasm . extrasystoles . hyperaemia on prolonged administration . hypertension . local irritation on prolonged administration . myocardial infarction (usually after use of 10% strength in patients with pre-existing cardiovascular disease) . oedema on prolonged administration . palpitation . photophobia . raised intraocular pressure . tachycardia . transient stinging

PREGNANCY Use only

INDICATIONS: As decongestant treatment of conjunctival hyperemia, minor allergic reactions of conjunctiva and lids, ulcerative, superficial and posttraumatic keratitis & certain herpetic keratitis

Cautions:

Asthma . cerebral arteriosclerosis (in adults) . corneal epithelial damage . darkly pigmented iris is more resistant to pupillary dilatation and caution should be exercised to avoid overdosage . diabetes (avoid eye drops in long standing diabetes) . mydriasis can precipitate acute angle-closure glaucoma in a few patients, usually over 60 years and hypermetropic (longsighted), who are predisposed to the condition because of a shallow anterior chamber . ocular hyperaemia . susceptibility to angleclosure glaucoma Phenylephrine may interact with systemically administered monoamine-oxidase inhibitors.

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