Dexamethasone

Indications & Dose:

Local treatment of inflammation (short-term)

TO THE EYE USING EYE DROP

Child: Apply 4–6 times a day

Adult: Apply every 30–60 minutes until controlled,

then reduced to 4–6 times a day

Short term local treatment of inflammation (severe conditions)

TO THE EYE USING EYE DROP

Child: Apply every 30–60 minutes until controlled,

reduce frequency when control achieved

Macular oedema following either branch retinal vein occlusion or central retinal vein occlusion (specialist use only) | Visual impairment due to diabetic macular oedema in adults who are pseudophakic, or who are insufficiently responsive to, or unsuitable for noncorticosteroid therapy (specialist use only) | For the treatment of inflammation of the posterior segment of the eye presenting as non-infectious uveitis (specialist use only)

BY INTRAVITREAL INJECTION

Adult: 700 micrograms, to be administered into the

affected eye, concurrent administration to both eyes not recommended. For further information on pretreatment, administration and repeat dosing, consult product literature

Contraindications:

With intravitreal use Active ocular herpes simplex . active or suspected ocular infection . active or suspected periocular infection . rupture of the posterior lens capsule in patients with aphakia, iris or transscleral fixated intra-ocular lens or anterior chamber intra-ocular lens . uncontrolled

advanced glaucoma

Side Effects:

Uncommon  With intravitreal use Eyelid pruritus . glaucoma . migraine . necrotising retinitis

Frequency not known When used by eye Corneal thinning . scleral thinning

With intravitreal use Blepharitis . cataract . headache . ocular hypertension . raised intra-ocular pressure . secondary ocular infection . visual disturbance

PREGNANCY Dexamethasone readily crosses the placenta.

With intravitreal use Manufacturer advises avoid unless potential benefit outweighs risk—no information

available.

Cautions:

With intravitreal use History of ocular viral infection (including herpes simplex) . posterior capsule tear or iris defect (risk of implant migration into the anterior chamber which may cause corneal oedema and, in persistent severe cases, the need for corneal transplantation) . retinal vein occlusion with significant retinal ischaemia

Precautions:

Interaction:

With intravitreal use Caution with concomitant

administration of anticoagulant or antiplatelet drugs— increased risk of haemorrhagic events.

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: