Choriogonadotropin alfa

Indications & Dose:

Reduction of intra-ocular pressure in ocular hypertension and open-angle glaucoma either as adjunct to betablockers or prostaglandin analogues or used alone in patients unresponsive to beta-blockers or if betablockers contra-indicated

TO THE EYE

Adult: Apply twice daily, then increased if necessary up to 3 times a day

Contraindications:

Hyperchloraemic acidosis

Side Effects:

Common or very common Corneal erosion . corneal oedema . dry mouth . headache . ocular disturbances . photophobia. reduced visual acuity . taste disturbances Uncommon Alopecia . amnesia . bradycardia . chest pain . cough . decreased libido . depression . diarrhoea . dizziness . drowsiness . dyspepsia . dyspnoea . epistaxis . erectile dysfunction . flatulence . malaise . nasal dryness . nausea . nervousness . oesophagitis . oral hypoaesthesia and paraesthesia . palpitation . paraesthesia . pharyngitis.renal pain . sinusitis . sleep disturbances . throat irritation . tinnitus . upper respiratory tract congestion . vomiting Frequency not known Arrhythmia . asthma . dermatitis . erythema .hypertension .peripheral oedema . rhinitis . tachycardia . tremor . vertigo

SIDE-EFFECTS

Systemic absorption can rarely cause sulfonamide-like side-effects and may require discontinuation if severe.

ALLERGY AND CROSS-SENSITIVITY Contra-indicated if history of sulfonamide hypersensitivity.

Cautions:

Renal tubular immaturity or abnormality. systemic absorption follows topical application

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

BREAST FEEDING Use only if benefit outweighs risk.

HEPATIC IMPAIRMENT Avoid.

RENAL IMPAIRMENT Avoid if eGFR less than 30 mL/minute/1.73m2.

PREGNANCY Avoid 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: