| ID | 222 |
|---|---|
| Name | BENZODIAZEPINE POISONING |
| Cause | |
| Signs Symptoms | |
| Diagnosis | |
| Investigations | |
| Management | Management: 1. All the emergency & supportive managements as for barbitnnte poisonning are applicable. Gastric lavage or activated charcoal should be considered within 1 hour of ingestion. Plus- 2. A specific antidot ‘flumazenil’ has been found a benzodiazepine receptor antagonist. Flumazenilis given slow i.v 0.2mg over 30-60 seconds repeated in O.Smg increments as needed up to a total dose of 3-5mg. It has no effect on barbiturate or other hypnotic receptors. Caution: Flumazenil may induce seizures in patients with preexisting seizure disorder, benzodiazepine addiction, or concomitant tricyclic antidepressant overdose. If seizures occur, diazepaim and other benzodiazepine anticonvulsants will not be effective. As with naloxone, the duration of action of flumazenil is short (2-3 hours) and resedation may occur, requiring repeated doses.1 3. Conscious level and oxygen saturation should be monitored for at least 6 hours after overdose (if the patient is admitted in a hospital with special care service). |
| Introduction | Background: Suicidal in middle class or upper class people. Fatal dose: 750mg (5mg tab. x150 or 10mg tab. x 75) |
| History | |
| Etiology | |
| Clinical Features | Clinical feature: 1. Drowsiness 2. Confusion 3. Disorientation 4. Ataxia |
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