Diseases List

ID 16
Name ABDOMINAL PAIN
Cause Causes of acute abdominal pain:2 A. Hyperacidity: Acute exacerbation of peptic ulcer. B. Inflammatory conditions: Acute gastro-enteritis, appendicitis, eolitis, diverticulitis, cholecystitis, hepatitis, pancreatitis, pyelonephritis, intra-abdominal abscess, pelvic inflammatory disease. C. Obstruction & stretching: Intestinal obstruction, biliary colic (due to obstruction of bile duct), ureteric colic (due to obstruction of ureteric duct). ; D. Perforation/rupture: Peptic ulcer, appendicitis, diverticular disease, ovarian cyst, aortic aneurysm. E. Loss of blood supply to an organ: Such as, Ischemic colitis.2 F. Other rare causes: Acute presentation of any extraintestinal causes of chronic or recurrent abdominal pain. Causes of chronic or recurrent abdominal pain:2 1. Gastro-intestinal causes: Dyspepsia, chronic peptic ulcer disease, amoebic and bacillary dysentery, enteric fever, irritable bowel syndrome (non-inflammatory), chronic inflammatory bowel diseases, malignant diseases of gastro-intestinal organs. Transformation of acute abdominal pain to chronic or recurrent abdominal pain, viz: Chronic gastro-enteritis, chronic appendicitis, chronic diverticulitis, chronic cholecystitis, chronic pancreatitis, chronic intestinal obstruction. 2. Extraintestinal causes of chronic or recurrent abdominal pain: Retroperitoneal- Aortic aneurysm, malignancy, lymphadenopathy, abscess. Metabolic/endocrine- Diabetes mellitus, Addison’s disease, acute intermittent porphyria, hypercalcemia. Locomotor- Vertebral compression, abdominal muscle strain. Hematological- Sickle-cell disease, hemolytic disorders. Neurological- Spinal cord lesions, radiculopathy, tabes dorsalis. Psychogenic- Depression, anxiety, hypochondriasis, somatisation. Drugs/toxins- Corticosteroids, lead, azathioprine, alcohol.
Signs Symptoms Seek immediate medical help if pain is accompanied by other worrisome signs and symptoms, including: Severe pain Fever Bloody stools Persistent nausea and vomiting Weight loss Skin that appears yellow Severe tenderness when you touch your abdomen Swelling of the abdomen
Diagnosis 1. Detailed history taking: Things to be considered: i. Initiation of pain (sudden or insidious ?). ii. Location of the pain. iii. pattern of the pain. iv. Duration of the pain. v. What makes the pain worse ? vi. What relieves the pain ? vii. Associated signs and symptoms. 2. Clinical examination: In initial assessment if there is signs of acute abdomen with peritonitis i.e presence of guarding and rebound tenderness with rigidity, patients should be resuscitated immediately and transferred to the hospital for operative management following minimal investigations. In cases of acute abdominal pain without sign of peritonitis, investigations should be done to reach a probable diagnosis for specific management.
Investigations 3. Investigations: i. Complete blood count - leucocytosis suggests inflammation or infection. ii. Blood urea and serum electrolytes - dehydration (?) iii. Serum amylase - acute pancreatitis (?) iv. Urine analysis (frequently done in the evaluation of abdominal pain), v. Liver enzymes- may be elevated in acute hepatitis, cholelithiasis, vi. Chest x-ray in erect posture - subdiaphramatic gas vii. Plain x-ray abdomen in erect posture- detection of fluid level (intestinal obstruction, abscess viii. Plain x-ray KUB region - renal or ureteric stone ix. Abdominal ultrasonogram - cholecystitis, cholelithiasis, pancreatitis, renal or ureteric stones, ovarian cyst, soft tissue mass, detection of fluid level (intestinal obstruction, abscess x. Endoscopic/Colonoscopic procedures: Endoscopy is useful for detecing ulcers, gastritis or stomach cancer. Colonoscopy or flexible sigmoidoscopy is useful for diagnosing infectious colitis, ulcerative colitis, or colon cancer. 4. Specialised investigations (if needed): i. CT Scan- pancreatitis, retroperitoneal collections or masses, aortic aneurysm ii. Endoscopic ultrasound is useful for diagnosing pancreatic cancer or gallstones if the standard ultrasound or CT or MRI scans fail to detect them, iii. ERCP (Endoscopic Retrograde Cholangio-Pancreatogfaphy)- to examine and find any pathology in the duodenum, the papilla of Vater, the bile ducts, the gallbladder and the pancreatic duct, iv. Mesenteric angiography - mesenteric ischemia 5. Diagnostic Laparoscopy/Surgery: In acute abdomen, where decision to operate remains in doubt even after appropriate investigations, diagnostic laparoscopy/surgery is advised. Chronic or recurrent abdominal pain: 1. Detailed history taking. 2. Clinical examination. 3. Routine investigations: i. Blood tests - Complete blood count, Blood sugar, ii. Urine routine examinations, iii. Stool routine examinations with ocult blood, iv. Chest x-ray P/A or A/P vew. 4. Specific investigations (as required): i. Liver function tests (S. bilirubin, ALT, AST). ii. Serum amylase - Chronic pancreatitis, Pancreatic cancer iii. Renal function tests - (B. urea, S. creatinine). v. Plain x-ray abdomen - any radio-opaque shadow (gallstone, renal stone Or, vi. Plain x-ray KUB region - Renal or ureteric stone vii. Barium meal x-ray - Peptic ulcer, upper g.i tract anomalies, viii. Endoscopy - Peptic ulcer, upper g.i tract anomalies, ix. Barium enema - Colonic obstruction x. Sigmoidoscopy, or colonoscopy - Colonic obstruction, irritable bowel syndrome, rectal bleeding, inflammatory bowel diseases xi. Abdominal ultrasonogram- Chronic cholecystitis, cholelithiasis, chronic pancreatitis, hepatic metastases, renal or ureteric stones, ovarian cyst, soft tissue mass, detection of fluid level (intestinal obstruction, abscess xii. IVU - Renal or ureteric stones, or stricture. 5. Specialised investigations (if needed): i. CT Scan- Pancreatitis, retroperitoneal collections or masses, aortic aneurysm ii. Mesenteric angiography - Mesenteric ischemia
Management Management:1,2 Acute abdominal pain: • General measures: i. Resuscitation of the patients - after initial assessment, adequate resuscitation should be done. - maintenance of hydration by i.v fluid. - nothing should be given by mouth until signs and symptoms of acute abdominal conditions are subsided. - relieve of acute pain by parenteral antispasmodic or narcotic analgesic. - observation of body temperature, pulse and heart rate, ii. In case of inflammatory conditions, appropriate broad-spectrum antibiotic can be started, iii. Patient should be transferred immediately to the hospital for further management. • Specific treatment: Treatments of common diseases causing acute abdominal pain have been discussed separately in the respective chapters. Chronic or Recurrent abdominal pain: General and specific management of common diseases causing chronic or recurrent abdominal pain have been discussed separately in this running and following respective chapters.
Introduction Abdominal pain is a frequent cause of human suffering in all age groups. This is a symptom manifested by different abdominal diseases and conditions of the organs within the abdominal cavity (i.e beneath the skin and muscles), which include mostly gastro-intestinal organs. Some times pain arising from organs that are colse to but not within the abdominal cavity, such as lower lungs, kidneys, uterus or ovaries are also referred to as abdominal pain. Abdominal pain may be presented as- i. Acute abdominal pain and ii. Chronic or recurrent abdominal pain. Acute abdominal pain accounts for about 5-10% of emergency medical visits in many hospitals and clinics. Depending on organ involvement and underlying causes abdominal pain 4 may be of several types, viz:2 1. Visceral pain: Pain originated in the gut and other abdominal organs in response to stimuli from inflammation, distension, contraction, torsion and stretching. Gut organs are usually insensitive to stimuli such as burning and cutting. 2. Parietal pain: Parietal peritoneum is innervated by somatic nerve fibres from the body wall. Stimulation of these nerve fibres by any cause or disease processes, e.g inflammation, infection or neoplasia, tends to produce a sharp, localised and lateralised pain. 3. Referred pain: In some cases abdominal pain is felt as referred to different specific organ or part of the body, e.g gall bladder pain is referred to the back and/or shoulder tip. 4. Psychogenicpain: Sometimes no organic cause can be identified. Cultural, emotional or psychosocial factors may be responsible for experiencing pain, e.g depression, anxiety or somatisation disorder etc.
History Chronic or recurrent abdominal pain: 1. Detailed history taking. 2. Clinical examination. 3. Routine investigations: i. Blood tests - Complete blood count, Blood sugar, ii. Urine routine examinations, iii. Stool routine examinations with ocult blood, iv. Chest x-ray P/A or A/P vew. 4. Specific investigations (as required): i. Liver function tests (S. bilirubin, ALT, AST). ii. Serum amylase - Chronic pancreatitis, Pancreatic cancer iii. Renal function tests - (B. urea, S. creatinine). v. Plain x-ray abdomen - any radio-opaque shadow (gallstone, renal stone Or, vi. Plain x-ray KUB region - Renal or ureteric stone vii. Barium meal x-ray - Peptic ulcer, upper g.i tract anomalies, viii. Endoscopy - Peptic ulcer, upper g.i tract anomalies, ix. Barium enema - Colonic obstruction x. Sigmoidoscopy, or colonoscopy - Colonic obstruction, irritable bowel syndrome, rectal bleeding, inflammatory bowel diseases xi. Abdominal ultrasonogram- Chronic cholecystitis, cholelithiasis, chronic pancreatitis, hepatic metastases, renal or ureteric stones, ovarian cyst, soft tissue mass, detection of fluid level (intestinal obstruction, abscess xii. IVU - Renal or ureteric stones, or stricture. 5. Specialised investigations (if needed): i. CT Scan- Pancreatitis, retroperitoneal collections or masses, aortic aneurysm ii. Mesenteric angiography - Mesenteric ischemia
Etiology Less serious causes of abdominal pain include constipation, irritable bowel syndrome, food allergies, lactose intolerance, food poisoning, and a stomach virus. Other, more serious, causes include appendicitis, an abdominal aortic aneurysm, a bowel blockage, cancer, and gastroesophageal reflux. Acute The various conditions that cause acute abdominal pain are usually accompanied by other symptoms that develop over hours to days. Causes can range from minor conditions that resolve without any treatment to serious medical emergencies, including: • Abdominal aortic aneurysm • Appendicitis • Cholangitis (bile duct inflammation) • Cholecystitis • Cystitis (bladder inflammation) • Diabetic ketoacidosis • Diverticulitis • Duodenitis (inflammation in the first part of the small intestine) • Ectopic pregnancy (in which the fertilized egg implants and grows outside of the uterus, such as in a fallopian tube) • Fecal impaction (hardened stool that can't be eliminated) • Heart attack • Injury • Intestinal obstruction • Intussusception (in children) • Kidney infection (pyelonephritis) • Kidney stones • Liver abscess (pus-filled pocket in the liver) • Mesenteric ischemia (decreased blood flow to the intestines) • Mesenteric lymphadenitis (swollen lymph nodes in the folds of membrane that hold the abdominal organs in place) • Mesenteric thrombosis (blood clot in a vein carrying blood away from your intestines) • Pancreatitis • Pericarditis (inflammation of the tissue around the heart) • Peritonitis (infection of the abdominal lining) • Pleurisy (inflammation of the membrane surrounding the lungs) • Pneumonia • Pulmonary infarction (loss of blood flow to the lungs) • Ruptured spleen • Salpingitis (inflammation of the fallopian tubes) • Sclerosing mesenteritis • Shingles • Spleen infection • Splenic abscess (pus-filled pocket in the spleen) • Torn colon • Urinary tract infection (UTI) • Viral gastroenteritis (stomach flu) Chronic (intermittent, or episodic) The specific cause of chronic abdominal pain is often difficult to determine. Symptoms may range from mild to severe, coming and going but not necessarily worsening over time. Conditions that may cause chronic abdominal pain include: • Angina (reduced blood flow to the heart) • Celiac disease • Endometriosis • Functional dyspepsia • Gallstones • Gastritis (inflammation of the stomach lining) • Gastroesophageal reflux disease (GERD) • Hiatal hernia • Inguinal hernia • Irritable bowel syndrome • Mittelschmerz (ovulation pain) • Ovarian cysts • Pelvic inflammatory disease (PID) • Peptic ulcer • Sickle cell anemia • Strained or pulled abdominal muscle • Ulcerative colitis (a type of inflammatory bowel disease) Progressive Abdominal pain that steadily worsens over time, often accompanied by the development of other symptoms, is usually serious. Causes of progressive abdominal pain include: • Cancer • Crohn's disease • Enlarged spleen (splenomegaly) • Gallbladder cancer • Hepatitis • Kidney cancer • Lead poisoning • Liver cancer • Non-Hodgkin's lymphoma • Pancreatic cancer • Stomach cancer • Tubo-ovarian abscess (pus-filled pocket involving a fallopian tube and an ovary) • Uremia (buildup of waste products in your blood)
Clinical Features Among the most important are nausea, vomiting, abdominal distention, diarrhea, constipation, obstipation, tarry stools, chills, fever, urinary frequency, hematuria, and jaundice.
Preventions Eating enough fibreand doing regular exercise can help prevent constipation and keep your bowels working well, which will prevent some forms of abdominal pain. It will also reduce your long-term risk of some diseases, such as diverticular disease or bowel cancer.
Treatment TREATMENT IS ACORDING TO CAUSE Bowel rest. Stop eating, or only eat easy-to-digest foods like crackers or bananas. Hydration. Drink plenty of water or a hydration formula. Heat therapy. Try a warm water bottle or a soak in the bath. Home remedies.
Complications In addition, many of the underlying conditions that cause abdominal pain can lead to serious complications, including the possibility of structural damage to the digestive system from infection, cancer and its treatments, and inflammatory bowel disease (IBD)
Prognosis AS PER Severity and Cause
Types 1. Uncomfortable bloating Possible cause: excess gas 2. Sharp pain in the lower right side of your abdomen Possible cause: appendicitis 3. Sharp stabbing pain in your upper right abdomen Possible cause: gallstones 4. Pain or burning in your upper middle abdominal Possible cause: peptic ulcer 5. General abdominal pain with diarrhea Possible cause: gastroenteritis 6. General abdominal pain with bloating Possible cause: irritable bowel syndrome (IBS) 7. Pain with bloody diarrhea Possible cause: Inflammatory bowel disease
Classification
Observation
Pathology
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406