Indications & Dose:

prophylaxis and treatment of seasonal allergic rhinitis including hay lever, managment of a associated sinus pain and pressure

DOSAGE AND ADMINISTRATION:

By the intranasal route 

Adults and children over 12 years of age:

For the prophylaxis and treatment of seasonal and allergic rhinitis. Two sprays into each nostril once a day, preferably in the morning. In some cases two sprays into each nostril twice daily may be required. The maximum daily dose should not exceed four sprays into each nostril.

Elderly: The normal adult dosage is applicable.

Children under 12 years of age: For the prophylaxis and treatment of seasonal allergic rhinitis and perennial rhinitis in children aged 4-11 years One spray into each nostril once a day, preferably in the morning. In some cases one spray into each nostril twice daily may be required. The maximum daily dose should not exceed two sprays into each nostril. For full therapeutic benefit regular usage is essential. The absence of an immediate effect should be explained to the patient, as maximum relief may not be obtained until after 3 to 4 days of treatment.

Contraindications:

Hypersensitivity to any of its ingredients

Cautions:

Precautions:

Interaction:

Drugs
• ritonavir ,Ketoconazole: Possible increased plasma fluticasone concentrations Labs

• Cholesterol: Increased 

SPECIAL CONSIDERATIONS

• Improvement following inhalation, 24 hr to 1-2 wk

• Systemic corticosteroid effects from inhaled and nasal steroids inadequate to prevent adrenal insufficiency in most patients withdrawn abruptly from corticosteroids

• Observe for evidence of inadequate adrenal response following periods of stress; use caution with extended use in children and adolescents as reduction in growth velocity may occur

PATIENT/FAMILY EDUCATION

• Rinsing the mouth following INH and using a spacer device reduces common

EENT adverse effects

• Review proper MDI administration technique regularly 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

SPECIAL WARNINGS AND SPECIAL PRECAUTIONS:

Local infection: 1 Infection of the airways should be appropriately treated but do not constitute a specific contra- indications to treatment with Fluticasone Propionate Aqueous Nasal Spray. The full benefit of FI uticasone Propionate Aqueous Nasal Spray may not been achieved until treatment has been administered for several days. Care must be taken while transferring patients from systemic steroid treatment to Fluticasone Propionate Aqueous Nasal Spray if there is any reason to suppose that there adrenal function is impaired. Although Fluticasone Propionate Aqueous Nasal Spray will control seasonal allergic rhinitis in most cases, an abnormally heavy challenge of summer allergens may in certain instances necessitate appropriate additional therapy, particularly to the control eye symptoms. Interaction with Other Medicinal Products and Other Forms of Interaction: Due to very low plasma concentration achieved after intranasal dosing, clinically significant drug interactions are unlikely. Care should be taken when co-administering known strong CYP3A4 inhibitors, e.g., ritonavir and ketoconazole as there is potential for increased systemic exposure to fluticasone propionate.

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: