Indications & Dose:
Metastatic castration-resistant prostate cancer in patients whose disease has progressed during or after treatment with a docetaxel-containing chemotherapy regimen (in combination with prednisone or prednisolone) | Metastatic castration-resistant prostate cancer in patients who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated (in combination with prednisone or prednisolone).
BY MOUTH
Adult: 1 g once daily for dose of concurrent prednisone or prednisolone-consult product literature
Contraindications:
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Cautions:
Diabetes (increased risk of hyperglycaemia-monitor blood sugar frequently). history of cardiovascular disease
Cardiovascular disease Correct hypertension and hypokalaemia before treatment (if significant risk of congestive heart failure such as history of cardiac failure, uncontrolled hypertension or cardiac events, consult product literature for management and increased monitoring).
Precautions:
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Interaction:
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Warnings:
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Adverse Effects:
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Lactations:
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Special Precautions:
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Counselling:
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Side Effects Or Adverse Reactions:
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Patient And Carer Advice:
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