Indications & Dose:

Rheumatoid Arthritis (RA)

Cryopyrin Associated Periodic Syndromes (CAPS)

DOSAGE 

Rheumatoid Arthritis (RA)

100 mg day administered daily by subcutaneous injection. The dose should be administered,at approximately the same time every day 

Cryopyrin Associated Periodic Syndromes (CAPS)

1-2 mg,kg daily for NOMID patients. The dose can be individually adjusted to a maximum of.8 mg,kg daily to control active inflammation. 

Contraindications:

Known hypersensitivity to E coli derived proteins, or to any component of the product. 

Cautions:

Precautions:

In RA, discontinue use if serious infection develops. 

Do not initiate in patients with active infections. 

Use in combination with Tumor Necrosis Factor (TNF) blocking agents is not recommended 

Hypersensitivity reactions, including anaphylactic reactions and angioedema, have been reported 

The impact of treatment with  on active and or chronic infections

and the development of malignancies is not known 

Live vaccines should not be given concurrently with  

Neutrophil counts should be assessed prior to initiating  treatment, and while receiving , monthly for 3 months, and thereafter quarterly for a period up to 1 year 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: