Drug Interaction Form

Drug Interactions Details

Product	Precaution	Interaction	Onset	Severity
CLOMIPRAMINE	Concurrent use of CLOMIPRAMINE and GRAPEFRUIT JUICE may result in increased risk of clomipramine toxicity.	GRAPEFRUIT JUICE	Delayed (after 24 hours)	Moderate (mayexacerbate patient’s condition)
CLOMIPRAMINE	Concurrent use of ETHANOL and CLOMIPRAMINE may result in enhanced drowsiness; impairment of motor skills.	ETHANOL	Rapid (within 24 hours)	Moderate (mayexacerbate patient’s condition)

Product

Precaution

Interaction

Onset

Severity

CLOMIPRAMINE

Concurrent use of CLOMIPRAMINE and GRAPEFRUIT JUICE may result in increased risk of clomipramine toxicity.

GRAPEFRUIT JUICE

Delayed (after 24 hours)

Moderate (mayexacerbate patient’s condition)

CLOMIPRAMINE

Concurrent use of ETHANOL and CLOMIPRAMINE may result in enhanced drowsiness; impairment of motor skills.

ETHANOL

Rapid (within 24 hours)

Moderate (mayexacerbate patient’s condition)

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