| Product | Precaution | Interaction | Onset | Severity |
|---|---|---|---|---|
| NIFEDIPINE | Concurrent use of NIFEDIPINE and GRAPEFRUIT JUICE may result in severe hypotension, myocardial ischemia, increased vasodilator side effects. | GRAPEFRUIT JUICE | Rapid (within 24 hours) | Major (possibly life threatening or potential permanent damage |
| NIFEDIPINE | Concurrent use of NIFEDIPINE and FOOD may result in increased or decreased peak concentrations. | FOOD | Rapid (within 24 hours) | Moderate (mayexacerbate patient’s condition) |
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