| Product | Precaution | Interaction | Onset | Severity |
|---|---|---|---|---|
| VERAPAMIL | Concurrent use of VERAPAMIL and GRAPEFRUIT JUICE may result in increased risk of verapamil adverse effects (flushing, edema, hypotension, myocardial ischemia). | GRAPEFRUIT JUICE | Rapid (within 24 hours) | Major (possibly life threatening or potential permanent damage |
| VERAPAMIL | Concurrent use of VERAPAMIL and CAFFEINE may result in increased caffeine serum concentrations and enhanced CNS stimulation. | CAFFEINE | Rapid (within 24 hours) | Moderate (mayexacerbate patient’s condition) |
| VERAPAMIL | Concurrent use of ETHANOL and VERAPAMIL may result in enhanced ethanol intoxication (impaired psychomotor functioning). | ETHANOL | Rapid (within 24 hours) | Moderate (mayexacerbate patient’s condition) |
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