Myasthenia Gravis

Alternate Name:

Test:

Response to cholinergic drugs (+), S.HLA-DR3(+), S.anti-AChR (FIT), electrophysiological stud­ies (AB), S.skeletal muscle antibodies (+)

Sign:

Ptosis, flaccid paralysis

Dd:

Hysteria, exhaustion, botulism, peripheral neu-ropathy, polymyositis, amyotrophic lateral sclero­sis, thymoma

Phys:

Abnormal fatigue state, particularly in cranial and ocular muscles, that is reversed by cholinergic drugs