Sjogren Syndrome

Alternate Name: Mikulices Disease

Test:

S.antinuciear antibodies (H), S.extractable nuclear antigen (H), S.HLA-DR3 (+), rheumatoid factor (+), Hb (L), WCC (L), ESR (H), B.eosino­phils (H), S.gamma-globulin (H), salivary gland opsy (AB)-

Sign:

Dd:

Rheumatoid arthritis, SLE, hepatobiliary disease,scleroderma, polymyositis, Hashimoto's disease, panarteritis

Phys:

Autoimmune disease of women characterised by dry eyes, mouth and vaginaMay affect mucous Membranes of any organ